Tottenham and Chelsea will square off for a place in the Carabao Cup final while Manchester City face Burton Albion in the other last-four tie.
A trio of Premier League clubs are left standing in the competition but at least one will be eliminated when Spurs – 2-0 winners at north London rivals Arsenal in the quarter-finals – take on Maurizio Sarri’s side, who edged Bournemouth 1-0 at Stamford Bridge.
Tottenham will host the Carabao Cup semi-final first leg as they seek to avenge the 2015 final defeat they suffered at the hands of the Blues.
Holders City, meanwhile, will be confident of securing a return to Wembley after being drawn against League One outfit Burton, who progressed on Tuesday courtesy of a 1-0 win away at Middlesbrough.
The first legs will take place in the week commencing January 7 with the reverse fixtures held a fortnight later.