The Nigeria international opened scoring for the Foxes with a calm finish in the 49th minute after he was teed up Youri Tielemans.
Iheanacho has now scored five goals in 16 league appearances for Leicester City this season.
The 23-year-old was replaced by Dennis Praet in the 64th minute.
His compatriot, Wilfred Ndidi was in action the home team for the entire duration of the game.
At the Old Trafford, Odion Ighalo featured for 10 minutes in Manchester United’s 5-2 home win against Bournemouth.
Ighalo replaced Marcus Rashford in the 80th minute.
The 31-year-old is still looking for his first league goal for the Red Devils.
Mason Greenwood (brace), Rashford, Anthony Martial and Bruno Fernandes scored for United in the game, while Junior Stanilas and Josh King were on target for the visitors.
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