Pierre-Emerick Aubameyang and Alexandre Lacazette are both set to miss Friday night’s Premier League opener for Arsenal.
The Gunners travel across the capital to take on Premier League newly-promoted club Brentford.
But Mikel Arteta looks set to be without both of his main strikers through illness.
As reported by The Athletic, the pair have gone down unwell just before the game and will miss the trip to West London.
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Fellow striker Eddie Nketiah has already been ruled out after injuring his ankle in the pre-season game against Chelsea.
It means Arteta is left short of options to lead the line with no senior recognised striker available.
Bukayo Saka or Gabriel Martinelli could be chosen up front despite their late returns after international duty, although Willian or Folarin Balogun are other options.
Thomas Partey and Gabriel Magalhaes are also sidelined through injury and will play no part against the Bees.
Partey, 28, injured the ligaments in his right ankle during the friendly with Chelsea, while Gabriel, 23, has an issue with his right knee.
Captain Aubemayang struggled for form last season, scoring just 15 goals in 39 appearances.
That was his lowest tally since the 2010-11 season when he played for Monaco and joined Saint-Etienne.
However, he played in all six of Arsenal’s friendlies this summer.
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