Four-time champions Enyimba were eliminated from the 2025 President Federation Cup by Abakaliki FC on Wednesday.
Abakaliki FC won the Round of 16 encounter played at the Stephen Keshi Stadium, Asaba 2-0.
Chukwudi Okoro opened scoring for the Nigeria National League, NNL, outfit one minute after the break.
Abakaliki FC doubled their advantage through Daniel Eni on the hour mark.
They will face Nasarawa United in the quarter-final.
At the Mobolaji Johnson, Arena, Onikan Lagos, Rangers recorded a 1-0 victory over Bendel Insurance.
Godwin Obaje netted the winning goal for the Flying Antelopes from the penalty spot late in the first half.
The Coal City club will confront Plateau United in the next round.
In Abuja, Akwa United defeated Inter Lagos 1-0 with Chisom Orji firing home the winning goal 18 minutes from time.
Kennedy Boboye’s men will keep a date with Kwara United in the last eight.
Elsewhere, Ikorodu City beat Beyond Limits 2-0 in a South West derby.
Two second half goals from Harison Austin and Shola Adelani separated both teams on the day.
The Oga Boys will lock horns with NNL outfit, Wikki Tourists in quarter-final.
Wikki Tourists booked a place in the last eight after edging past Warri Wolves 4-3 on penalities.
The game ended 1-1 in regulation time.
Quarter-Final Fixtures
Abakaliki FC Vs Nasarawa United
Wikki Tourists Vs Ikorodu City
Akwa United Vs Kwara United
Plateau United Vs Rangers Int’l
By Adeboye Amosu